Significance of Pharmacokinetic

Pharmacokinetic is telling a variety of ways (such as intravenous injection, intravenous injection, oral administration, etc.) in which drugs go through into the body for the absorption, distribution, metabolism and excretion, which is A.D.M.E. The development and application of pharmacokinetic in recent years have proved it a special and important position in the field of pharmacy it occupied. First of all, pharmacokinetic, as a means to deal with the mathematical analysis of scientific medicine dynamic processes in the body, has the significant theory value. It is an important part of “mathematics pharmacy”. Its basic analysis method has been infiltrated into the biological pharmacy, clinical pharmacy, drug therapy, clinical pharmacology, molecular pharmacology, biochemistry analytical chemistry, pharmacology and toxicology, pharmacy and many other areas of science, becoming the most and main foundation of those subjects, promoting their vigorous development. At the same time, pharmacokinetic has a very wide range of practical significance.
Its development will be existing in drug evaluation, improvement of pharmaceutical dosage form, new drugs’ active design, providing efficient, quick, effective, low toxic and side effects drugs, as well as the guidance of clinical rational drug use. Through the study of the pharmacokinetic, it plays important role in the effective blood drug concentration of clinical treatment, the optimal dose, dosing cycle, calculation of loading dose, and whether continuous medication would occur accumulation in vivo. In a word, pharmacokinetics has become a useful new tool, widely used in the pharmaceutical field and various disciplines. A technical report of the United Nations WHO has stressed that: “For the evaluation of drug efficacy and toxicity, pharmacokinetic, not only in the preclinical pharmacological study stage, but also all stages of drug discoveries shows important value.”