Clinical Pharmacology Discussion Solutions

Clinical Pharmacology Discussion Solutions
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Clinical Pharmacology Discussion Solutions
Clinical Pharmacology / 3371126. Which of the following antibiotics is the choice in treatment of moderately resistant enterococcus endocarditis? A. Penicillin B. Penicillin plus streptomycin
C. Penicillin plus Chloromycetin
D. Vancomycin
E. Ristocetin
1 127. The total body content of iron in the normal adult is betweenA. 5 and 10 mg
B. 50 and 100 gm
C. 25 and 50 gm
D. 2 and 5 gm
E. 0.5 and 1.5 gm
1 128. The treatment of choice for chronic myelocytic leukemia withhigh white count is A. daunomycin
B. prophylactic antibiotics C. radiotherapy D. leukapheresis
E. busulfan (Myleran)
1129. All of the following result in a cholestatic type of hepatitis in drug-sensitive individuals EXCEPT
A. methimazole (Tapazole)
B. chlorpropamide (Diabinese) C. chlorpromazine (Thorazine) D. methyl testosterone
E. carbon tetrachloride
1130. Antidiuretic hormone acts by
A. increasing the permeability of the proximal renal tubuleto water
B. increasing the permeability of the distal renal tubule towater
C. decreasing the glomerular filtration rate D. increasing sodium excretion
E. causing active reabsorption of water from the loop ofHenle
338 / Clinical Pharmacology
1131. Iodine not utilized in the thyroid gland is removed from theplasma by way of
A. fecal excretion
B. urinary excretion C. sweat glands D. salivary glands
E. gastric glands
Clinical Pharmacology Discussion Solutions
1132. Methimazole (Tapazole) interferes with thyroid functionmainly by
A. inhibition of iodine uptake
B. inhibition of thyroidal organic-binding and couplingreactions C. immunologic means
D. destruction of thyroid cells E. the same mechanism as perchlorate
1 133. The drug of choice in the treatment of acute gouty arthritis is A. probenecid
B. colchicine C. aspirin D. corticotropin
E. phenylbutazone
1134. A lupuslike picture may follow the administration of
A. diphenylhydantoin
B. estrogens C. hydralazine D. ergotamine
E. Mustargen
1135. Common methods of therapy for allergic rhinitis include allof the following EXCEPT
A. antihistamines
B. corticosteroids C. antimalarials D. change of environment
E. desensitization
Clinical Pharmacology 3391136. An effective agent for the treatment of superficial fungal in- fections is A. tetracycline
B. amphotericin B
C. potassium permanganate
I), griseofulvin
E. neomycine
1137. Ampicillin (alpha-aminoben/yl penicillin) is A. not effective orally
B. not inactivated by penicillinase C. acid stable D. not effective against coliform organisms
E. not allergenic
I13K. The treatment of trichinosis is A. stilbamidine
B. sulfanilamide
C. thional
I). ACTH
E. nonspecific and supportive
1139. Barbiturate overdosage is treated by all of the followingEXCEPT
A. forced diuresis
B. gastric lavage
C. cathartics D. positive pressure respiration
E. dialysis
1 140. Untoward side effects of phenothiazines include all of the fol- lowing EXCEPT
A. sensory loss B. parkinsonismlike symptoms
C. dystonic movements
I), hypotensive episodes
E. convulsive seizures
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