Effects Of Nonfenalne Therapy Questions

Effects Of Nonfenalne Therapy Questions
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Complete elimination of
nomlfenalne can be achieved In:
(a) 4-8 hours.
(b) 24-39 hours.
(c) 48-72 hours.
(d) 75-95 hours.
4. Metabolltea of nomlfenalne:
(a) are formed by hydroxylation and
methoxylation.
(b) account for 50 percent of the
administered dose.
(c) are more active than the parent
compound.
(d) have not been detected in
plasma.
5. With regard to clinical
effectlvene.., nomHenalne la:
(a) superior to placebo.
(b) at least as effective as
imipramine.
(c) not effective in children.
(d) Both a and b are correct.
6. When taken In overdose,
nomlfenalne:
(a) produces marked cardiac
changes.
(b) may cause drowsiness and
tremor.
(c) has a high incidence of
convulsions.
(d) usually causes coma and death.
7. The Incidence of anticholinergic
aide effects aaaoclated with
nomlfenalne therapy la:
(a) twice that of imipramine.
(b) about half that of imipramine.
(c) the same as imipramine.
(d) None of the above is true.
8. Epileptic patlenta who take
nomlfenalne:
(a) should lower their dosage of
anticonvulsants.
(b) should increase their dosage of
anticonvulsants.
(c) do not show an increase in
convulsion frequency.
(d) need no anticonvulsant
medication.
9. The oral dosege range for
nomlfenalne la:
(a) 10-50 mgld.
(b) 50-200 mg/d.
(c) 200-400 mg/d.
(d) 400-800 mg/d.
10. All of the following statementa are
true except:
(a) nomifensine is suitable for
ambulatory patients.
(b) nomifensine has a relative lack
of cardiotoxicity.
(c) nomifenslne has minimal
anticholinergic and sedative side
effects.
(d) nomifensine may precipitate
convulsions, even at low doses.
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