Treatment For Primary Torsion Dystonia Discussion

Treatment For Primary Torsion Dystonia Discussion
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Treatment For Primary Torsion Dystonia Discussion
Question 1
What anti-epileptic drug is recommended for a child with epilepsy and
co-morbid attention deficit hyperactivity disorder (ADHD)? Can Ritalin
safely be used for treatment?
Question 105
What is the difference in efficacy and pharmacokinetics between sodium
valproate and valproic acid?
Question 106
Is it safe to give valproic acid to infants below 12 months of age?
Question 107
How many times must the liver transaminases (SGOT and SGPT) rise to
justify a discontinuation of valproic acid therapy in children? Which of
these enzymes is more sensitive and reliable in this situation?
Question 108
1. Does valproic acid block the photosensitivity phenomenon in reflex
epilepsy?
2. Can a patient with this photosensitivity be safely exposed to computer
games or other photic stimuli when receiving valproic acid treatment?
3. Does the photosensitivity phenomenon occur in partial seizures?
Question 109
1. Can an epileptic fit be induced in idiopathic and symptomatic focal
epilepsy syndromes by flickering lights?
2. Is valproate effective against the photosensitive phenomenon (seizure
induction by flickering light)?
Question 110
How much time should one give before a loading dose of phenytoin is
judged to be ineffective in controlling seizures and an alternative should
be instituted?
Question 111
What is the maintenance dose of phenytoin in seizures arising as a
complication of chronic renal failure?
Question 112
I know that the loading dose of phenytoin in status epilepticus is
20 mg/kg with an upper limit of 1000 mg but if the same situation arose
as a complication of chronic renal failure (on regular dialysis), should
this dose remain the same or be reduced? If reduced, what should the
dose be?
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Treatment For Primary Torsion Dystonia Discussion
Question 113
1. What is the most effective antiepileptic for a patient with simple
partial motor status epilepticus who is not responding to a loading
dose of phenytoin?
2. How long does phenytoin, given in a loading dose, take to work?
Question 114
Is valproate effective if given rectally in status epilepticus and, if so, what
dose is recommended?
Question 115
In simple partial motor status epilepticus, if the patient does not respond
to diazepam and phenytoin, is it justifiable to proceed to anaesthetic
medication?
Question 116
What is the recommended upper limit dose of lamotrigine when
combined with both carbamazepine and valproate?
Question 117
Is a valproate–lamotrigine combination more effective than
carbamazepine on its own against partial seizures?
Question 118
Why is the incidence of parkinsonism less common in smokers?
Question 119
Is it recommended to start the treatment of parkinsonism with dopamine
agonists alone in elderly (over 60 years old) patients, and to delay using
L-dopa until the disease has progressed much further? Is there a rationale
for this protocol in younger patients?
Question 120
Does amantadine increase the endogenous release of dopamine, thus
aiding early treatment of parkinsonism?
Question 121
A 25-year-old woman, pregnant in her second trimester, starts to
experience chorea and bilateral ankle arthralgia but has no past history of
rheumatic chorea. In the first hour, her erythrocyte sedimentation rate is
70. Could this be no more than chorea gravidarum?
Question 122
Is valproate as equally effective as haloperidol in the treatment of chorea,
in particular rheumatic chorea?
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